GABA
What is GABA?
Gamma-Aminobutyric Acid (GABA) is a neurotransmitter naturally produced in the brain that plays a crucial role in regulating neuronal excitability. It functions by inhibiting nerve transmission in the central nervous system, which helps induce relaxation and reduce anxiety.
What are the Benefits of GABA?
Anxiety Reduction: GABA is known for its calming effects, making it beneficial for reducing symptoms of anxiety and promoting relaxation.
Improved Sleep: It may help improve sleep quality by calming the mind and promoting deeper, more restful sleep.
Mood Stabilization: GABA may help stabilize mood by modulating neurotransmitter activity in the brain.
Stress Management: It assists in managing stress by reducing the physiological responses associated with stress.
What Research is on GABA?
Research on GABA includes studies examining its effects on anxiety, sleep disorders, and neurological health:
- Anxiety: Clinical trials have demonstrated that GABA supplementation can reduce symptoms of anxiety disorders.
- Sleep: Studies suggest that GABA may help improve sleep quality and reduce the time it takes to fall asleep.
- Neurological Disorders: Research is ongoing to explore GABA's potential in treating conditions like epilepsy and Parkinson's disease.
What is the Mechanism of Action for GABA?
Neurotransmitter Regulation: GABA acts by binding to GABA receptors in the brain, which inhibits the transmission of nerve impulses, resulting in a calming effect.
Alpha Wave Modulation: It increases alpha brain waves, associated with relaxation and mental alertness.
Stress Response: GABA helps regulate the body's response to stress by reducing the activity of the sympathetic nervous system.
What is the Typical Dosage of GABA?
Typical dosages of GABA in dietary supplements range from 250 mg to 750 mg per day, taken in divided doses or as a single dose before bedtime.
What Foods are Rich in GABA?
GABA is not abundant in natural food sources. However, small amounts of GABA can be found in fermented foods such as kimchi, miso, and certain types of yogurt due to the fermentation process.
Koh, Wuhyun et al. “GABA tone regulation and its cognitive functions in the brain.” Nature reviews. Neuroscience vol. 24,9 (2023): 523-539. doi:10.1038/s41583-023-00724-7
Braga, Jason D et al. “Gamma-aminobutyric acid as a potential postbiotic mediator in the gut-brain axis.” NPJ science of food vol. 8,1 16. 2 Apr. 2024, doi:10.1038/s41538-024-00253-2