What is Apigenin?

Apigenin is a naturally occurring flavonoid found in many fruits, vegetables, and herbs. It is known for its antioxidant and anti-inflammatory properties and has been studied for its potential health benefits.

What are the Benefits of Apigenin?

Antioxidant Activity: Apigenin scavenges free radicals and reduces oxidative stress, protecting cells from damage.

Anti-inflammatory: It has anti-inflammatory effects, which may help reduce inflammation and alleviate symptoms of inflammatory conditions.

Cancer Prevention: Apigenin shows promise in inhibiting the growth of cancer cells and promoting apoptosis (cell death) in various types of cancers.

Brain Health: Some research suggests that apigenin may support brain health and cognitive function.

What Research is on Apigenin?

Research on apigenin includes studies on its potential health benefits:

  1. Cancer: Preclinical studies have shown that apigenin may inhibit the progression of cancer by targeting multiple cellular pathways.
  2. Cardiovascular Health: Apigenin may help protect against cardiovascular disease by improving blood vessel function and reducing inflammation.
  3. Neuroprotective Effects: Early research indicates that apigenin may have neuroprotective properties, potentially reducing the risk of neurodegenerative diseases.

What is the Mechanism of Action for Apigenin?

Antioxidant Properties: Apigenin scavenges free radicals, preventing oxidative damage to cells and tissues.

Anti-inflammatory Activity: It inhibits inflammatory mediators and pathways, reducing inflammation throughout the body.

Cancer Cell Inhibition: Apigenin interferes with processes involved in cancer cell proliferation and survival, promoting apoptosis and inhibiting metastasis.

What is the Typical Dosage of Apigenin?

There is no established typical dosage of apigenin as it is primarily consumed through dietary sources like fruits and vegetables. In supplement form, dosages can vary widely based on the product.

What Foods are Rich in Apigenin?

Apigenin is found in various plant-based foods, including:

  1. Parsley
  2. Celery
  3. Chamomile Tea
  4. Oranges
  5. Onions
  6. Broccoli


Zhu, Lin et al. “Research progress on antisepsis effect of apigenin and its mechanism of action.” Heliyon vol. 9,11 e22290. 15 Nov. 2023, doi:10.1016/j.heliyon.2023.e22290

Oh, Hyeon-Muk et al. “Experimental evidence for anti-metastatic actions of apigenin: a mini review.” Frontiers in oncology vol. 14 1380194. 7 Mar. 2024, doi:10.3389/fonc.2024.1380194