MSM (Methylsulfonylmethane)
What is MSM?
Methylsulfonylmethane (MSM) is a naturally occurring sulfur compound found in various foods and produced in small amounts by the human body. It is commonly used as a dietary supplement due to its potential health benefits, particularly for joint health and anti-inflammatory properties.
What are the benefits of MSM?
MSM is known for its anti-inflammatory and antioxidant properties. It may help reduce joint pain and stiffness, improve skin health, alleviate allergy symptoms, and support overall immune function. Some studies also suggest potential benefits for hair and nail health.
What research is on MSM?
Research on MSM has demonstrated its efficacy in reducing pain and inflammation associated with osteoarthritis and other joint disorders. A study highlighted MSM's role in promoting melanogenesis via JNK activation, suggesting potential applications for skin health and treating conditions like vitiligo. Further research is ongoing to explore its broader therapeutic effects and mechanisms of action.
What is the mechanism of action for MSM?
MSM is believed to work by providing biologically active sulfur, which plays a crucial role in various physiological processes, including the formation of connective tissues and antioxidant defense systems. MSM's anti-inflammatory effects are mediated through the modulation of cytokine production and the inhibition of inflammatory pathways.
What is the typical dosage of MSM?
The typical dosage of MSM varies depending on the condition being treated, but common dosages range from 1,000 to 3,000 milligrams per day. It is often taken in divided doses with meals. Higher dosages should be monitored by healthcare professionals to ensure safety and efficacy.
What foods are rich in MSM?
MSM is found in small amounts in a variety of foods, including:
- Fruits and vegetables (e.g., tomatoes, corn)
- Grains
- Milk
- Coffee
- Tea
However, the levels of MSM in foods are generally low, and supplementation is often necessary to achieve therapeutic doses.
Kim, In Wook et al. “Methylsulfonylmethane promotes melanogenesis via activation of JNK in Mel-Ab cells.” International journal of cosmetic science, 10.1111/ics.12988. 24 Jun. 2024, doi:10.1111/ics.12988