Vitamin C

What is Vitamin C?

Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that is essential for the growth, development, and repair of tissues in the body. It is also an important antioxidant, which means it helps to protect the body from damage caused by free radicals.

Vitamin C is found naturally in many fruits and vegetables, including citrus fruits, strawberries, kiwi fruit, broccoli, Brussels sprouts, and red and green peppers. It can also be taken as a dietary supplement in the form of tablets, capsules, or powders.

Vitamin C is important for a variety of bodily functions, including the production of collagen, which is a key component of connective tissue, bone, and skin. It also plays a role in wound healing, the absorption of iron, and the maintenance of healthy immune function.

What are the benefits of Vitamin C?

Vitamin C has many benefits for the body, some of which include:

  1. Boosting the immune system: Vitamin C is known to help support the immune system by stimulating the production of white blood cells, which can help fight off infections.
  2. Collagen production: Vitamin C is important for the production of collagen, which is essential for healthy skin, bones, and connective tissue.
  3. Antioxidant activity: Vitamin C is a powerful antioxidant, which means it can help protect the body from damage caused by harmful molecules called free radicals.
  4. Improved iron absorption: Vitamin C can help the body absorb iron from plant-based sources of food, which can be particularly beneficial for vegetarians and vegans.
  5. Reduced risk of chronic disease: Some studies have suggested that a diet rich in vitamin C may be associated with a lower risk of chronic diseases such as heart disease, stroke, and certain types of cancer.
  6. Improved eye health: Vitamin C may also help reduce the risk of cataracts and age-related macular degeneration, two common eye conditions that can lead to vision loss.
  7. Reduced inflammation: Vitamin C has been shown to have anti-inflammatory properties, which may help reduce inflammation in the body and improve overall health.

What research is on Vitamin C?

There is a considerable amount of research on vitamin C, also known as ascorbic acid. Here are some of the areas of research on vitamin C:

  1. Immune system support: Vitamin C is known to support the immune system, and research has shown that it can reduce the severity and duration of colds and other respiratory infections.
  2. Antioxidant properties: Vitamin C is a potent antioxidant that helps protect cells from damage caused by free radicals.
  3. Cardiovascular health: Vitamin C has been found to improve blood pressure, reduce inflammation, and decrease the risk of heart disease.
  4. Skin health: Vitamin C is essential for the production of collagen, which is a key component of healthy skin. Research has shown that vitamin C can help improve skin texture, reduce the appearance of fine lines and wrinkles, and protect against sun damage.
  5. Cancer prevention: Some studies have suggested that vitamin C may have a protective effect against certain types of cancer, particularly those of the digestive tract.
  6. Wound healing: Vitamin C is necessary for the formation of new tissue, and research has shown that it can help speed up the healing process of wounds and injuries.
  7. Mental health: Vitamin C may play a role in the prevention and treatment of certain mental health conditions, such as depression and anxiety.

What is the mechanism of action of Vitamin C?

Vitamin C, also known as ascorbic acid, is an essential vitamin that plays an important role in many physiological processes. Its mechanism of action can be explained as follows:

    1. Antioxidant: Vitamin C is a powerful antioxidant that helps protect cells from damage caused by harmful molecules called free radicals. Free radicals can cause oxidative stress, which can lead to cellular damage and contribute to the development of diseases such as cancer, heart disease, and diabetes. Vitamin C helps neutralize free radicals by donating electrons to them, making them less reactive and harmful.
    2. Collagen synthesis: Vitamin C is necessary for the synthesis of collagen, a structural protein that is essential for the formation and maintenance of connective tissues such as skin, bones, and cartilage. Vitamin C acts as a co-factor in the enzymatic reactions that convert pro-collagen into mature collagen, helping to maintain the strength and elasticity of these tissues.
    3. Immune system support: Vitamin C plays a role in the functioning of the immune system by supporting the production and activity of white blood cells, which are essential for fighting infections and diseases. Vitamin C also enhances the production of antibodies, proteins that help identify and neutralize foreign invaders in the body.
    4. Iron absorption: Vitamin C helps enhance the absorption of iron from plant-based foods, such as spinach and beans, by converting non-heme iron into a form that is more easily absorbed by the body. This is particularly important for people who follow a vegetarian or vegan diet, as they may be at risk of iron deficiency.

What is the typical dosage of Vitamin C?

The typical recommended daily dosage of Vitamin C varies based on age and gender. The National Institutes of Health (NIH) provide the following recommended dietary allowances (RDAs) for Vitamin C:

  1. Infants 0-6 months: 40 milligrams (mg)
  2. Infants 7-12 months: 50 mg
  3. Children 1-3 years: 15 mg
  4. Children 4-8 years: 25 mg
  5. Children 9-13 years: 45 mg
  6. Teenage boys 14-18 years: 75 mg
  7. Teenage girls 14-18 years: 65 mg
  8. Adult men: 90 mg
  9. Adult women: 75 mg
  10. Pregnant women: 85 mg
  11. Breastfeeding women: 120 mg

It's important to note that some people, such as smokers and people with certain medical conditions, may require higher doses of Vitamin C. It's always best to consult with a healthcare provider before taking any supplements or drastically changing your diet.

Xu, Kedi et al. “Vitamin C intake and multiple health outcomes: an umbrella review of systematic reviews and meta-analyses.” International journal of food sciences and nutrition vol. 73,5 (2022): 588-599. doi:10.1080/09637486.2022.2048359