What is Pterostilbene?

Pterostilbene is a natural compound found in many fruits. It is structurally similar to resveratrol, another antioxidant found in red wine. Pterostilbene is known for its potent antioxidant and anti-inflammatory properties, and it is used to support cardiovascular health, cognitive function, and longevity.

What are the Benefits of Pterostilbene?

Antioxidant: Pterostilbene protects cells from oxidative damage by neutralizing free radicals.

Anti-inflammatory: It reduces inflammation and supports overall health, particularly in conditions like cardiovascular disease and metabolic syndrome.

Cognitive Function: Pterostilbene may improve brain health and cognitive function, potentially reducing the risk of neurodegenerative diseases.

What Research is on Pterostilbene?

Research on pterostilbene includes:

  1. Cancer Prevention: Studies show that pterostilbene has potential anti-cancer properties, including inhibiting cancer cell growth and inducing apoptosis.
  2. Cognitive Health: Research suggests that pterostilbene can improve cognitive function, protect against neurodegenerative diseases, and enhance brain health.
  3. Cardiovascular Health: Pterostilbene has been shown to improve heart health by reducing oxidative stress, lowering blood pressure, and improving lipid profiles.

What is the Mechanism of Action for Pterostilbene?

Antioxidant Activity: Pterostilbene neutralizes free radicals and reduces oxidative damage to cells.

Gene Expression Modulation: It influences genes involved in inflammation, metabolism, and cell cycle regulation, providing protective effects against various diseases.

Lipid Metabolism: Pterostilbene improves lipid metabolism, reducing cholesterol levels and supporting cardiovascular health.

What is the Typical Dosage of Pterostilbene?

Typical dosages of pterostilbene range from 50-150 mg per day. It is often combined with other antioxidants like resveratrol to enhance its effects.

What Foods are Rich in Pterostilbene?

Pterostilbene is found in:

  1. Blueberries: The richest natural source of pterostilbene.
  2. Grapes: Contain moderate amounts of pterostilbene.
  3. Peanuts: Also a source of this compound, though in smaller quantities.

Qu, Xin et al. “Pterostilbene as a Therapeutic Alternative for Central Nervous System Disorders: A Review of the Current Status and Perspectives.” Journal of agricultural and food chemistry vol. 71,40 (2023): 14432-14457. doi:10.1021/acs.jafc.3c06238

Özyalçın, Büşra, and Nevin Sanlier. “Antiobesity pathways of pterostilbene and resveratrol: a comprehensive insight.” Critical reviews in food science and nutrition, 1-9. 24 Jul. 2023, doi:10.1080/10408398.2023.2238319